Assistant Professor - Department of Neuroscience Assistant Professor - Menninger Department of Psychiatry & Behavioral Sciences Ph.D., Harvard University, 2006 One Baylor Plaza Baylor College of Medicine Houston TX, 77030 Telephone: 713-798-3018 - Fax: 713-798-3946 Email: phchiu@bcm.tmc.edu Website: pchiu.cpu.bcm.edu

How is it that a depressed individual may value nothing at all, whereas an addict might value drug consumption at the expense of all else?  To address this and related questions, Dr. Chiu’s laboratory examines the neurobiology of human reward-processing and social decision-making.  The lab’s work focuses on how such processes may be perturbed and rehabilitated in psychiatric populations.  Ongoing projects use multiple converging methods (e.g., behavior, self-report, clinical interviews, computational models, EEG, fMRI) to: 1) identify neural circuitry involved in normative reward-guided decision-making; 2) specify how these pathways go awry in clinical populations marked by deficits in valuation and volition (e.g., major depression, schizophrenia, addiction, autism); and 3) develop biologically-informed interventions by which these functional deficits may be remediated.

Current collaborative work examines the neural dynamics of social behavior in autism using hyperscan-fMRI, a technique that allows the simultaneous measurement of brain activity in socially interacting people.  In collaboration with members of the Computational Psychiatry Unit, Dr. Chiu is also engaged in the design and implementation of real-time fMRI neurofeedback to facilitate therapeutic response in psychiatric illness.

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Montague, PR & Chiu, PH (2009) Brain reward and fMRI. In D. Charney & E. Nestler (Eds.), Neurobiology of Mental Illness, Oxford University Press: pp 846-866.

Chiu, PH, Holmes, AJ, Pizzagalli, DA (2008) Dissociable recruitment of rostral anterior cingulate and inferior frontal cortex in emotional response inhibition. NeuroImage 42: 988-997.

Chiu, PH, Lohrenz, TM, Montague, PR (2008) Smokers' brains compute but ignore a fictive error signal in a sequential investment task. Nature Neuroscience 11: 514-520.

Chiu, PH, Kayali, MA, Kishida, KT, Tomlin, D, Klinger, LG, Klinger, M, Montague, PR (2008) Self responses along cingulate cortex reveal quantitative neural phenotype for high functioning autism.  Neuron 57: 463-473.

Chiu, PH & Deldin, PJ (2007) Neural evidence for enhanced error detection in major depressive disorder. American Journal of Psychiatry 164: 608-616.

Montague, PR & Chiu, PH (2007) For goodness' sake. [News and Views] Nature Neuroscience 10: 137-138.

Deldin, PJ & Chiu, PH (2005) Cognitive restructuring and EEG in major depression. Biological Psychology 70: 141-151.

Ambady, N, Chiao, J, Chiu, P, Deldin, PJ (2005) Race and emotion: Insights from a social neuroscience perspective. In JT Cacioppo, PS Visser, CL Pickett (Eds.), Social Neuroscience: People Thinking About People, MIT Press: pp 209-228.

Chiu, PH, Ambady, N, Deldin, PJ (2004) CNV to emotional in- and out-group stimuli differentiates high- and low- prejudiced individuals. Journal of Cognitive Neuroscience 16: 1030-1039.

Deldin, PJ, Shestyuk, A, Chiu, PH (2003) ERP indices of memory biases in depression. In M. Lenzenweger and J. Hooley (Eds.), Principles of Experimental Psychopathology, American Psychological Association: pp 195-210.

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2004-2005 Graduate Society Dissertation Merit Fellowship, Harvard University

2005-2006 American Psychological Association Postdoctoral Fellowship (T32-MH18882)

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