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Brown Foundation Professor - Department of Neuroscience
Professor - Menninger Department of Psychiatry and Behavioral Sciences
Director - Human Neuroimaging Laboratory
Ph.D., University of Alabama at Birmingham School of Medicine, 1988
One Baylor Plaza
Baylor College of Medicine
Houston TX, 77030
Telephone: 713-798-3134 - Fax: 713-798-3946
Email: read@bcm.edu
Website: www.hnl.bcm.tmc.edu
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Research InterestsWork in the Montague lab focuses on computational neuroscience - the connection between the physical mechanisms present in real neural tissue and the computational functions that these mechanisms embody. Computational descriptions present the possibility of connecting cognition to underlying biological processes that implement it. In this sense, computational approaches to neural function provide a unifying language for understanding neural function at a variety of levels. The Montague group uses computational models to design and understand experimental probes of brain function ranging from detailed measurements of neurotransmitter delivery to social interactions amongst small groups of interacting humans. In recent years, work in the Montague group has used mathematically contrived games in combination with computational models of reward learning to understand the neural underpinnings of decision-making and to probe a range of neuropathologies including addiction (Chiu et al., 2008), developmental disorders like Autism Spectrum Disorder (Lohrenz et al., 2007; Chiu et al., 2008), and personality disorders (King-Casas et al., 2008).
Selected PublicationsKing-Casas, B, Sharp, C, Lomax, L, Lohrenz, T, Fonagy, P, Montague, PR (2008) The rupture and repair of cooperation in borderline personality disorder. Science. 321:806-810. PDF SOM Podcast Perspective Rangel, A, Camerer, C, Montague, PR (2008) A framework for studying the neurobiology of value-based decision making. Nature Reviews Neuroscience 9:545-556. PDF Chiu, PH, Lohrenz, TM, Montague, PR (2008) Smokers' brains compute, but ignore, a fictive error signal in a sequential investment task. Nature Neuroscience 11(4):514-520. PDF SOM Chiu, PH, Kayali, MA, Kishida, KT, Tomlin, D, Klinger, LG, Klinger, MR, Montague, PR (2008) Self responses along cingulate cortex reveal quantitative neural phenotype for high-functioning autism. Neuron 57: 463-473. PDF Preview SOM Tomlin, D, Kayali, MA, King-Casas, B, Anen, C, Camerer, CF, Quartz, SR, Montague, PR (2006) Agent-specific responses in cingulate cortex during economic exchanges. Science 312:1047-1050 PDF Supplementary Materials King-Casas, B, Tomlin, D, Anen, C, Camerer, CF, Quartz, SR, Montague, PR (2005) Getting to know you: Reputation and trust in a two-person economic exchange. Science 308:78-83. PDF Commentary Supplementary Materials Montague, PR, Hyman, SE, Cohen, JD (2004) Computational roles for dopamine in behavioural control. Nature 431:760-767. PDF Schultz, W, Dayan, P, Montague, PR (1997) A neural substrate of prediction and reward. Science 275:1593-1599. PDF Montague, PR, Dayan, P, Sejnowski, TJ (1996) A framework for mesencephalic dopamine systems based on predictive hebbian learning. J. Neuroscience 16(5):1936-1947. PDF Montague, PR, Dayan, P, Person, C, Sejnowski, TJ (1995) Bee foraging in uncertain environments using predictive Hebbian learning. Nature 377:725-728 PDF. (News and Views 683-684 PDF).
Awards, Recognition, Appointments, and HonorsMember, Institute for Advanced Study, Princeton, NJ 2005-2006
Current Graduate Students- Josepheen De Asis Cruz (Neuroscience)
- Ann Harvey (Neuroscience)
- Ting Xiang (Neuroscience)
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